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View larger Compound SC-1
AT22424
CAS 1313019-65-6
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $100.30 | Total: $501.50 |
| 1 | 10 | $84.96 | Total: $849.60 |
| 1 | 25 | $71.98 | Total: $1,799.50 |
| 1 | 50 | $61.36 | Total: $3,068.00 |
| 1 | 100 | $53.10 | Total: $5,310.00 |
Data sheet
| Molecular Formula | C21H13ClF3N3O2 |
| Molecular Weight | 431.8 |
| CAS Numbers | 1313019-65-6 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | FC(F)(F)C1=CC(NC(=O)NC2=CC=C(OC3=CC=C(C=C3)C#N)C=C2)=CC=C1Cl |
| References | Chun-Yu Liu, et al. Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells. Breast Cancer Res. 2013;15[4] R63. |
More info
Compound SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. Compound SC-1 potently inhibits the phosphorylation of STAT3 by blocking STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular carcinoma cell lines[1].