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GSK3987 (LXRα/β Agonist)
AOB8048
CAS: 264206-85-1
Chemical Name: 1-Benzyl-3-(4-methoxyanilino)-4-phenylpyrrole-2,5-dione
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $22.05 | Total: $2,205.00 |
| 1 | 50 | $25.48 | Total: $1,274.00 |
| 1 | 25 | $29.89 | Total: $747.25 |
| 1 | 10 | $35.28 | Total: $352.80 |
| 1 | 5 | $41.65 | Total: $208.25 |
Data sheet
| Molecular Formula | C24H20N2O3 |
| Molecular Weight | 384.44 |
| CAS Numbers | 264206-85-1 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | GSK3987; LXRα/β Agonist |
| IUPAC/Chemical Name | 1-Benzyl-3-(4-methoxyanilino)-4-phenylpyrrole-2,5-dione |
| InChl Key | HLZMYWLMBBLASX-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H20N2O3/c1-29-20-14-12-19(13-15-20)25-22-21(18-10-6-3-7-11-18)23(27)26(24(22)28)16-17-8-4-2-5-9-17/h2-15,25H,16H2,1H3 |
| SMILES Code | O=C(C(NC1=CC=C(OC)C=C1)=C2C3=CC=CC=C3)N(CC4=CC=CC=C4)C2=O |
| References | 1) Ranganathan PV, et al., Netrin-1-treated macrophages protect the kidney against ischemia-reperfusion injury and suppress inflammation by inducing M2 polarization. Am J Physiol Renal Physiol. 2013 Apr 1;304(7):F948-57. 2) Lin HR. Paeoniflorin acts as a liver X receptor agonist. J Asian Nat Prod Res. 2013;15(1):35-45. doi: 10.1080/10286020.2012.742510. Epub 2013 Jan 3. PubMed PMID: 23281636. 3) Jaye MC, et al. Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure. J Med Chem. 2005 Aug 25;48(17):5419-22. PubMed PMID: 16107141. |
More info
Potent and specific liver X receptor (LXR) dual agonist of LXRalpha and LXRbeta
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