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Bisindolylmaleimide V
AOB5920
CAS: 113963-68-1
Chemical Name: Ro 31-6045; BIM-V; 3,4-Di-1H-indol-3-yl-1-methyl-1H-pyrrole-2,5-dione
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $16.65 | Total: $1,665.00 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 5 | $31.45 | Total: $157.25 |
Data sheet
| Molecular Formula | C16H20N6O |
| Molecular Weight | 312.37 |
| CAS Numbers | 1092578-47-6 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMF 20 mg per mL, DMF PBS (pH 7.2) (1:9) 0.1 mg per mL, DMSO 20 mg per mL, Ethanol 20 mg per mL |
| Purity | 98% by HPLC |
| Synonym | BIM V, Ro 31-6045, R8009 |
| IUPAC/Chemical Name | 3,4-di-1H-indol-3-yl-1-methyl-1H-pyrrole-2,5-dione |
| InChl Key | SWAWYMIKGOHZMR-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C21H15N3O2/c1-24-20(25)18(14-10-22-16-8-4-2-6-12(14)16)19(21(24)26)15-11-23-17-9-5-3-7-13(15)17/h2-11,22-23H,1H3 |
| SMILES Code | O=C1C(=C(c2c[nH]c3ccccc23)C(=O)N1C)c1c[nH]c2ccccc12 |
| References | 1) Lazareno, S., Popham, A., and Birdsall, N.J.M. Muscarinic interactions of bisindolylmaleimide analogues. European Journal of Pharmacology 360, 281-284 (1998). 2) Toullec, D., Pianetti, P., Coste, H., et al. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266(24), 15771-15781 (1991). |
More info
Weak inhibitor of protein kinase C (PKC), blocking the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo