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Aloisine (RP-106)

AOB5673

CAS No:496864-15-4

Chemical Name: Aloisine RP106; 7-Butyl-6-(4-methoxy-phenyl)-5H-pyrrolo[2,3-b]pyrazine

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$21.00

$21.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $9.45 Total: $945.00
150 $10.92 Total: $546.00
125 $12.81 Total: $320.25
110 $15.12 Total: $151.20
15 $17.85 Total: $89.25

Data sheet

Molecular FormulaC17H19N3O
Molecular Weight281.35
CAS Numbers496864-15-4
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name7-butyl-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine
InChl KeyWVMANZPBOBRWCB-UHFFFAOYSA-N
InChl CodeInChI=1S/C17H19N3O/c1-3-4-5-14-15(12-6-8-13(21-2)9-7-12)20-17-16(14)18-10-11-19-17/h6-11H,3-5H2,1-2H3,(H,19,20)
SMILES CodeCOC(C=C1)=CC=C1C2=C(CCCC)C3=NC=CN=C3N2
References1) Mettey, Y., Gompel, M., Thomas, V., et al. Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects. J. Med. Chem. 46(2), 222-236 (2003).

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Selective, potent, ATP-competitive inhibitor of CDK1/cyclin B, CDK5/p25, and GSK-3