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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $64.60 | Total: $323.00 |
| 1 | 10 | $54.72 | Total: $547.20 |
| 1 | 25 | $46.36 | Total: $1,159.00 |
| 1 | 50 | $39.52 | Total: $1,976.00 |
| 1 | 100 | $34.20 | Total: $3,420.00 |
Overview
IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling by inhibiting MAPK and p65 NF-?B phosphorylation, as well as the expression of TLR4-dependent proinflammatory proteins. It also prevents the development of experimental abdominal aortic aneurysm.
Chemical Properties
| Molecular Formula | C35H71NO5 |
| Molecular Weight | 585.94 |
| CAS Numbers | 1115270-63-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCCCCCCCCCCCCCO[C@H]1[C@H](O)[C@@H](CN)O[C@H](OC)[C@@H]1OCCCCCCCCCCCCCC |
Storage and Handling
0C Short Term, -20C Long Term
References
Huggins C, et al. A novel small molecule TLR4 antagonist [IAXO-102] negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development. Atherosclerosis. 2015 Oct;242[2] 563-70.