Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $24.65 | Total: $123.25 |
| 1 | 10 | $20.88 | Total: $208.80 |
| 1 | 25 | $17.69 | Total: $442.25 |
| 1 | 50 | $15.08 | Total: $754.00 |
| 1 | 100 | $13.05 | Total: $1,305.00 |
Overview
CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-
Chemical Properties
| Molecular Formula | C17H15NO2 |
| Molecular Weight | 265.31 |
| CAS Numbers | 2165340-32-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1ccc2c(ccnc2c1)-c1ccc(O)c(C)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Zhang S , Hu Z , Tanji H , et al. Small-molecule inhibition of TLR8 through stabilization of its resting state[J]. Nature Chemical Biology, 2017, 14[1] 58-64.