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Overview
Chloranil (tetrachloro-p-benzoquinone) triggers inflammation and neurological dysfunction through Toll-like receptor 4 signaling and can be used to model inflammation in mice.
Chemical Properties
| Molecular Formula | C6Cl4O2 |
| Molecular Weight | 245.88 |
| CAS Numbers | 118-75-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | ClC1=C(Cl)C(=O)C(Cl)=C(Cl)C1=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Fu J,et al. The acute exposure of tetrachloro-p-benzoquinone [a.k.a. chloranil] triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling The protective role of melatonin preconditioning. Toxicology. 2017 Apr 15;381 39-50.