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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $49.30 | Total: $246.50 |
| 1 | 10 | $41.76 | Total: $417.60 |
| 1 | 25 | $35.38 | Total: $884.50 |
| 1 | 50 | $30.16 | Total: $1,508.00 |
| 1 | 100 | $26.10 | Total: $2,610.00 |
Overview
SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.
Chemical Properties
| Molecular Formula | C22H17F4N3O2 |
| Molecular Weight | 431.38 |
| CAS Numbers | 181629-93-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc2CCN(C(=O)Nc3cc(F)cc(c3)-c3cccnc3)c2cc1C(F)(F)F |
Storage and Handling
0C Short Term, -20C Long Term
References
Bromidge SM, et al. Biarylcarbamoylindolines are novel and selective 5-HT[2C] receptor inverse agonists identification of 5-methyl-1-[[2-[[2-methyl-3-pyridyl]oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline [SB-243213] as a potential antidepressantanxiolytic agent. J Med Chem. 2000 Mar 23;43[6] 1123-34.