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Overview
Nicardipine hydrochloride (YC-93 Hydrochloride) is the hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator.
Chemical Properties
| Molecular Formula | C26H30ClN3O6 |
| Molecular Weight | 515.99 |
| CAS Numbers | 54527-84-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C1(=C(C(C(=C(N1)C)C(=O)OC)c1cc(ccc1)[N+](=O)[O-])C(=O)OCCN(C)Cc1ccccc1)C.Cl |
Storage and Handling
0C Short Term, -20C Long Term
References
Harino S, et al. Invest Ophthalmol Vis Sci, 1992, 33[10], 2885-2890.