Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $93.50 | Total: $467.50 |
| 1 | 10 | $79.20 | Total: $792.00 |
| 1 | 25 | $67.10 | Total: $1,677.50 |
| 1 | 50 | $57.20 | Total: $2,860.00 |
| 1 | 100 | $49.50 | Total: $4,950.00 |
Overview
SAK3 is a novel modulator of nAChR activity that enhances T-type voltage-gated Ca2+ channel (T-VGCC) activity, and has potentiating effects on both Cav3.1 and Cav3.3 T-type Ca2+ channel currents.SAK3 is neuroprotective against scopolamine-induced cholinergic dysfunction in human neuroblastoma SH-SY5Y cells.SAK3 is used for the study of memory deficits and Alzheimer's disease. SAK3 can be used to study memory deficits and Alzheimer's disease.
Chemical Properties
| Molecular Formula | C20H23N3O4 |
| Molecular Weight | 369.41 |
| CAS Numbers | 1256269-87-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(OCC)C=1C(=O)CC2(C(=O)N=C3C(=CC=CN32)C)C1N4CCCCC4 |
Storage and Handling
0C Short Term, -20C Long Term
References
Yasushi Yabuki, et al. Pharmacological properties of SAK3, a novel T-type voltage-gated Ca2+ channel enhancer. Neuropharmacology. 2017 May 1;117 1-13.