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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $84.15 | Total: $420.75 |
| 1 | 10 | $71.28 | Total: $712.80 |
| 1 | 25 | $60.39 | Total: $1,509.75 |
| 1 | 50 | $51.48 | Total: $2,574.00 |
| 1 | 100 | $44.55 | Total: $4,455.00 |
Overview
Pozanicline hydrochloride is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline hydrochloride is an ?4?2-selective nAChR agonist, which binds to rat brain ?4?2 nAChR with a Ki of 17 nM while binding to ?7 nAChR is insignificant[2].
Chemical Properties
| Molecular Formula | C11H17ClN2O |
| Molecular Weight | 228.72 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H]Cl.CC1=NC=CC=C1OC[C@H]2NCCC2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Lin NH, et al. Structure-activity studies on 2-methyl-3-[2[S]-pyrrolidinylmethoxy] pyridine [ABT-089] an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties. J Med Chem. 1997 Jan 31;40[3] 385-90.