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- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $211.65 | Total: $1,058.25 |
| 1 | 10 | $179.28 | Total: $1,792.80 |
| 1 | 25 | $151.89 | Total: $3,797.25 |
| 1 | 50 | $129.48 | Total: $6,474.00 |
| 1 | 100 | $112.05 | Total: $11,205.00 |
Overview
TMP-153 is a novel and potent ACAT inhibitor with an IC50 value of 5-10 nM for intestinal and hepatic ACAT in animals.TMP-153 has a hypocholesterolemic effect, inhibiting cholesterol uptake and lowering plasma cholesterol in rats and hamsters.
Chemical Properties
| Molecular Formula | C24H18ClF2N3O |
| Molecular Weight | 437.87 |
| CAS Numbers | 128831-46-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(NC1=CC=C(F)C=C1F)NC2=CN=C3C=C(C(=CC3=C2C=4C=CC=CC4Cl)C)C |
Storage and Handling
0C Short Term, -20C Long Term
References
Sugiyama Y, et al. TMP-153, a novel ACAT inhibitor, inhibits cholesterol absorption and lowers plasma cholesterol in rats and hamsters. Atherosclerosis. 1995 Feb;113[1] 71-8.