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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $36.55 | Total: $182.75 |
| 1 | 10 | $30.96 | Total: $309.60 |
| 1 | 25 | $26.23 | Total: $655.75 |
| 1 | 50 | $22.36 | Total: $1,118.00 |
| 1 | 100 | $19.35 | Total: $1,935.00 |
Overview
PNU-282987 (free base) is a potent agonist of ?7 nicotinic acetylcholine receptor (nAChR) with an EC50 of 154 nM and a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. It can be used for central and peripheral nervous system studies[1].
Chemical Properties
| Molecular Formula | C14H17ClN2O |
| Molecular Weight | 264.75 |
| CAS Numbers | 711085-63-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Clc1ccc(cc1)C(=O)N[C@H]1CN2CCC1CC2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Bodnar AL,et al. Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. J Med Chem. 2005 Feb 24;48[4] 905-8.