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MDL-800
AOB17344
CAS: 2275619-53-7
Chemical Name: Methyl 2-(N-(5-bromo-4-fluoro-2-methylphenyl)sulfamoyl)-5-((3,5-dichlorophenyl)sulfonamido)benzoate
1859 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Overview
First-in-class cellularly active SIRT6 allosteric activator
Chemical Properties
| Molecular Formula | C21H16BrCl2FN2O6S2 |
| Molecular Weight | 626.29 |
| CAS Numbers | 2275619-53-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | Methyl 2-(N-(5-bromo-4-fluoro-2-methylphenyl)sulfamoyl)-5-((3,5-dichlorophenyl)sulfonamido)benzoate |
| InChl Key | FKFQBYBODAKGOA-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C21H16BrCl2FN2O6S2/c1-11-5-18(25)17(22)10-19(11)27-35(31,32)20-4-3-14(9-16(20)21(28)33-2)26-34(29,30)15-7-12(23)6-13(24)8-15/h3-10,26-27H,1-2H3 |
| SMILES Code | O=C(OC)C1=CC(NS(=O)(C2=CC(Cl)=CC(Cl)=C2)=O)=CC=C1S(=O)(NC3=CC(Br)=C(F)C=C3C)=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
MDL800; MDL 800; MDL-800
References
Huang Z, Zhao J, Deng W, Chen Y, Shang J, Song K, Zhang L, Wang C, Lu S, Yang X, He B, Min J, Hu H, Tan M, Xu J, Zhang Q, Zhong J, Sun X, Mao Z, Lin H, Xiao M, Chin YE, Jiang H, Xu Y, Chen G, Zhang J. Identification of a cellularly active SIRT6 allosteric activator. Nat Chem Biol. 2018 Dec;14(12):1118-1126. doi: 10.1038/s41589-018-0150-0. Epub 2018 Oct 29. PubMed PMID: 30374165.
