Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $46.75 | Total: $233.75 |
| 1 | 10 | $39.60 | Total: $396.00 |
| 1 | 25 | $33.55 | Total: $838.75 |
| 1 | 50 | $28.60 | Total: $1,430.00 |
| 1 | 100 | $24.75 | Total: $2,475.00 |
Overview
Phe-Lys(Trt)-PAB is a cathepsin-cleavable linker used in the development of antibody-drug conjugates (ADCs), serving as a crucial component for releasing therapeutic agents within targeted cells.
Chemical Properties
| Molecular Formula | C41H44N4O3 |
| Molecular Weight | 640.81 |
| CAS Numbers | 1116085-99-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(NCCCC[C@@H](C(NC1=CC=C(CO)C=C1)=O)NC([C@H](CC2=CC=CC=C2)N)=O)(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5 |
Storage and Handling
0C Short Term, -20C Long Term
References
Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20[2] 390-6.