Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Overview
Fmoc-Lys-OH hydrochloride is an alkyl-chain-based PROTAC linker and a non-cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs).
Chemical Properties
| Molecular Formula | C21H25ClN2O4 |
| Molecular Weight | 404.89 |
| CAS Numbers | 139262-23-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(N[C@H](C(O)=O)CCCCN)OCC1C2=CC=CC=C2C3=CC=CC=C13.Cl |
Storage and Handling
0C Short Term, -20C Long Term
References
Nalawansha DA, et al. PROTACs An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27[8] 998-985.