L748337

L748337

AT22905

CAS 244192-94-7

More details

1000 Items

$93.60

$93.60 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $61.20 Total: $306.00
110 $51.84 Total: $518.40
125 $43.92 Total: $1,098.00
150 $37.44 Total: $1,872.00
1100 $32.40 Total: $3,240.00

Overview

L748337 is a competitive and potent ?3-adrenoceptor antagonist that inhibits the action of ?3-, ?2-, and ?1-adrenoceptors, activates MAPK signaling, promotes phosphorylation of Erk12, and inhibits the protective effects of CL316243, and is used in the study of disorders caused by abnormalities of the ?3-adrenoceptors.

Chemical Properties

Molecular FormulaC26H31N3O5S
Molecular Weight497.61
CAS Numbers244192-94-7
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(=O)NCc1cccc(OC[C@@H](O)CNCCc2ccc(NS(=O)(=O)c3ccccc3)cc2)c1

Storage and Handling

0C Short Term, -20C Long Term

References

S Neidhold, et al. The function of alpha- and beta-adrenoceptors of the saphenous artery in caveolin-1 knockout and wild-type mice. Br J Pharmacol. 2007 Feb;150[3] 261-70.