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PKUMDL-WQ-2101
AOB8011
CAS: 304481-72-9 (2095878-12-7)
Chemical Name: (E)-2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide
14995 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $9.35 | Total: $46.75 |
| 1 | 10 | $7.92 | Total: $79.20 |
| 1 | 25 | $6.71 | Total: $167.75 |
| 1 | 50 | $5.72 | Total: $286.00 |
| 1 | 100 | $4.95 | Total: $495.00 |
Overview
Novel selective allosteric inhibitor of PHGDH and serine synthesis with anti-tumor activity, binding to site I
Chemical Properties
| Molecular Formula | C14H11N3O6 |
| Molecular Weight | 317.25 |
| CAS Numbers | 304481-72-9 (2095878-12-7) |
| Solubility | Soluble to 100 mM in DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (E)-2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide |
| InChl Key | OXONIXZPWKJHMW-VIZOYTHASA-N |
| InChl Code | InChI=1S/C14H11N3O6/c18-10-2-3-11(13(20)6-10)14(21)16-15-7-8-5-9(17(22)23)1-4-12(8)19/h1-7,18-20H,(H,16,21)/b15-7+ |
| SMILES Code | O=C(N/N=C/C1=CC([N+]([O-])=O)=CC=C1O)C2=CC=C(O)C=C2O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
PKUMDL WQ 2101
References
Wang et al (2017) Rational design of selective allosteric inhibitors of PHGDH and serine synthesis with anti-tumor activity. Cell Chem.Biol. 24 55 PMID: 28042046