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JAY2-22-33
AOB2333
CAS: 121489-14-3
Chemical Name: JAY-2-22-33; 2-(Methyl-pyridin-3-ylmethyl-amino)-ethanol
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.95 | Total: $114.75 |
| 1 | 10 | $19.44 | Total: $194.40 |
| 1 | 25 | $16.47 | Total: $411.75 |
| 1 | 50 | $14.04 | Total: $702.00 |
| 1 | 100 | $12.15 | Total: $1,215.00 |
Overview
Novel neuroprotective agent, significantly reducing Aβ toxicity by delaying paralysis and improving cognitive performances in a transgenic mouse model of AD
Chemical Properties
| Molecular Formula | C9H14N2O |
| Molecular Weight | 166.22 |
| CAS Numbers | 121489-14-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2-(methyl(pyridin-3-ylmethyl)amino)ethan-1-ol |
| InChl Key | AONUOBNHKYQJIO-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C9H14N2O/c1-11(5-6-12)8-9-3-2-4-10-7-9/h2-4,7,12H,5-6,8H2,1H3 |
| SMILES Code | CN(CCO)CC1=CC=CN=C1 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
JAY2-22-33; JAY2 22 33; JAY22233; JAY-2-22-33; JAY 2 22 33
References
1) Keowkase R, Aboukhatwa M, Adam BL, Beach JW, Terry AV Jr, Buccafussco JJ, Luo Y. Neuroprotective effects and mechanism of cognitive-enhancing choline analogs JWB 1-84-1 and JAY 2-22-33 in neuronal culture and Caenorhabditis elegans. Mol Neurodegener. 2010 Dec 16;5:59.
2) Buccafusco JJ, Beach JW, Terry AV Jr. Desensitization of nicotinic acetylcholine receptors as a strategy for drug development. J Pharmacol Exp Ther. 2009 Feb;328(2):364-70