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2-PMAP
AOB1080
CAS No: 102212-26-0
Chemical Name: 2-[[(o-Hydroxyphenyl)amino]methyl]pyridine
500 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $11.05 | Total: $55.25 |
| 1 | 10 | $9.36 | Total: $93.60 |
| 1 | 25 | $7.93 | Total: $198.25 |
| 1 | 50 | $6.76 | Total: $338.00 |
| 1 | 100 | $5.85 | Total: $585.00 |
Overview
Novel modulator of amyloid precursor protein expression, reducing β-amyloid deposition
Chemical Properties
| Molecular Formula | C12H12N2O |
| Molecular Weight | 200.24 |
| CAS Numbers | 102212-26-0 |
| Solubility | DMSO |
| IUPAC/Chemical Name | 2-[(2-pyridinylmethyl)amino]-phenol |
| InChl Key | GXJRVWZNMZGWAQ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C12H12N2O/c15-12-7-2-1-6-11(12)14-9-10-5-3-4-8-13-10/h1-8,14-15H,9H2 |
| SMILES Code | OC1=CC=CC=C1NCC2=NC=CC=C2 |
Storage and Handling
4C at solid form for three years
Synonyms
ARN2966
References
1) Yodeji Asuni, et al. An APP translation modulator ARN2966 reduces BETA-AMYLOID deposition and prevents memory deficits in ALZHEIMER'S DISEASE transgenic mice. Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 2012.
2) Asuni, A.A., Guridi, M., Pankiewicz, J.E., et al. Modulation of APP expression reduces Aβ deposition in a mouse model. Ann. Neurol. 75(5), 684-699 (2014).