Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
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- Molecular Probes
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- Alzheimer's Disease
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $211.65 | Total: $1,058.25 |
| 1 | 10 | $179.28 | Total: $1,792.80 |
| 1 | 25 | $151.89 | Total: $3,797.25 |
| 1 | 50 | $129.48 | Total: $6,474.00 |
| 1 | 100 | $112.05 | Total: $11,205.00 |
Overview
RO7185876 is a selective gamma secretase modulator, which can be used in the study of Alzheimer's disease.
Chemical Properties
| Molecular Formula | C25H28F3N7 |
| Molecular Weight | 483.532 |
| CAS Numbers | 2226038-71-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C=1N=C2[C@@H](CCCCN2N1)C3=C(F)C(F)=C(F)C=C3)[C@H]4[C@@]5(CN(C[C@]4(CC5)[H])C=6C=C(C)N=CN6)[H] |
Storage and Handling
0C Short Term, -20C Long Term
References
Ratni H, et al. Discovery of RO7185876, a Highly Potent ?-Secretase Modulator [GSM] as a Potential Treatment for Alzheimer's Disease. ACS Med Chem Lett. 2020 Apr 27;11[6] 1257-1268.