Primaquine diphosphate

Primaquine diphosphate

AT0850

CAS 63-45-6

More details

999 Items

$35.00

$35.00 per 500 mg

Overview

Primaquine diphosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the properties of protozoal DNA. This agent eliminates tissue (exo-erythrocytic) malarial infection, preventing the development of the erythrocytic forms of the parasite which are responsible for relapses in Plasmodium vivax and ovale malaria. Primaquine is active against late hepatic stages (hypnozoites, schizonts).

Chemical Properties

Molecular FormulaC15H21N3O
Molecular Weight455.34
CAS Numbers63-45-6
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(CCCN)Nc1c2c(cc(c1)OC)cccn2.OP(=O)(O)O.OP(=O)(O)O

Storage and Handling

0C Short Term, -20C Long Term

References

Vale N, et al. Eur J Med Chem, 2009, 44[3], 937-953.

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