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Overview
Rafoxanide as a dual CDK46 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.
Chemical Properties
| Molecular Formula | C19H11Cl2I2NO3 |
| Molecular Weight | 626.01 |
| CAS Numbers | 22662-39-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(NC1=CC(Cl)=C(OC2=CC=C(Cl)C=C2)C=C1)(=O)C3=C(O)C(I)=CC(I)=C3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Shi X, Li H, Shi A et al.Discovery of rafoxanide as a dual CDK46 inhibitor for the treatment of skin cancer[J].Oncol Rep. 2018 Sep;40[3] 1592-1600.