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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $48.45 | Total: $242.25 |
| 1 | 10 | $41.04 | Total: $410.40 |
| 1 | 25 | $34.77 | Total: $869.25 |
| 1 | 50 | $29.64 | Total: $1,482.00 |
| 1 | 100 | $25.65 | Total: $2,565.00 |
Overview
PfDHODH-IN-2 is a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH, IC50 : 1.11 ?M) inhibitor . It is used an antimalarial agent and can be used for the research of malaria
Chemical Properties
| Molecular Formula | C13H12ClNO3S |
| Molecular Weight | 297.76 |
| CAS Numbers | 425629-94-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCOC(=O)C1=C(Nc2ccc(Cl)cc2)SCC1=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Minghao Xu, et al. Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase discovery and optimization of dihydrothiophenone derivatives. J Med Chem. 2013 Oct 24;56[20] 7911-24.