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Overview
Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species.
Chemical Properties
| Molecular Formula | C18H20FN3O4 |
| Molecular Weight | 361.37 |
| CAS Numbers | 82419-36-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)OCC(C)N3C=C1C(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Divo AA, et al. Antimicrob Agents ChemOthers. 1988 Aug;32[8] 1182-6.