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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $107.95 | Total: $539.75 |
| 1 | 10 | $91.44 | Total: $914.40 |
| 1 | 25 | $77.47 | Total: $1,936.75 |
| 1 | 50 | $66.04 | Total: $3,302.00 |
| 1 | 100 | $57.15 | Total: $5,715.00 |
Overview
FBA-IN-1 (compound 2a11) is a first-in-class, covalent, and allosteric inhibitor of fructose-1,6-bisphosphate aldolase (FBA) from Candida albicans (CaFBA). Additionally, FBA-IN-1 inhibits the growth of Azole-resistant strains 103 with an MIC 80 of 1 ?gmL [1].
Chemical Properties
| Molecular Formula | C15H13NOSe |
| Molecular Weight | 302.23 |
| CAS Numbers | 2605897-57-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1C=2C=CC=CC2[Se]N1C3=CC=C(C=C3)CC |
Storage and Handling
0C Short Term, -20C Long Term
References
Wen W,et al. Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis. J Med Chem. 2022 Feb 10;65[3] 2656-2674.