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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $67.15 | Total: $335.75 |
| 1 | 10 | $56.88 | Total: $568.80 |
| 1 | 25 | $48.19 | Total: $1,204.75 |
| 1 | 50 | $41.08 | Total: $2,054.00 |
| 1 | 100 | $35.55 | Total: $3,555.00 |
Overview
SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the expression of the tumor suppressor gene PTEN. expression, inhibiting the protein expression of PI3K and AKT.
Chemical Properties
| Molecular Formula | C24H21F2N5O2S |
| Molecular Weight | 481.52 |
| CAS Numbers | 1019169-83-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=S(=O)(NC1=CC=C(C=C1)NC=2N=C(N=C(C2)NC3=CC=C(C=C3)C)C)C4=CC=C(F)C=C4F |
Storage and Handling
0C Short Term, -20C Long Term
References
Liu, Yayun, et al. Novel squalene epoxidase inhibitor and application thereof in preparation of anti-liver cancer drugs. China, CN116987037. 2023-11-03.