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Overview
Molnupiravir (MK-4482) (EIDD-2801) is a prodrug of the ribonucleoside analog EIDD-1931 which is orally bioavailable. Molnupiravir can be used in COVID-19, seasonal and pandemic influenza research that has broad spectrum antiviral activity against multiple coronaviruses and influenza virus, for example, SARS-CoV-2, MERS-CoV, SARS-CoV [1][2].
Chemical Properties
| Molecular Formula | C13H19N3O7 |
| Molecular Weight | 329.31 |
| CAS Numbers | 2492423-29-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=NO)[nH]c1=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Sheahan TP, et al. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Sci Transl Med. 2020 Apr 6. pii eabb5883.