Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Molecular Probes
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- Cancer Research
- Epigenetics
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- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
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- Proteins and Antibodies
- Primary Cells
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- Rare Chemicals
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- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $70.55 | Total: $352.75 |
| 1 | 10 | $59.76 | Total: $597.60 |
| 1 | 25 | $50.63 | Total: $1,265.75 |
| 1 | 50 | $43.16 | Total: $2,158.00 |
| 1 | 100 | $37.35 | Total: $3,735.00 |
Overview
A2ti-2 is a low affinity and selective inhibitor of the membrane-bound protein A2S100A10 heterotetramer (A2t) (IC50 : 230 ?M).A2ti-2 exhibits antiviral activity by selectively disrupting protein interactions between A2 and S100A10, and protects against human papillomavirus type 16 (HPV16) infection.
Chemical Properties
| Molecular Formula | C18H18N4O2S |
| Molecular Weight | 354.43 |
| CAS Numbers | 482646-13-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1ccccc1OCc1nnc(SCC(N)=O)n1-c1ccccc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Tummala R K Reddy, et al.Three-dimensional Pharmacophore Design and Biochemical Screening Identifies Substituted 1,2,4-triazoles as Inhibitors of the Annexin A2-S100A10 Protein Interaction. ChemMedChem. 2012 Aug;7[8] 1435-46.