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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $79.05 | Total: $395.25 |
| 1 | 10 | $66.96 | Total: $669.60 |
| 1 | 25 | $56.73 | Total: $1,418.25 |
| 1 | 50 | $48.36 | Total: $2,418.00 |
| 1 | 100 | $41.85 | Total: $4,185.00 |
Overview
GLP-26, an HBV capsid assembly regulator (CAM), inhibits HBV DNA replication (IC50=3 nM) in the Hep AD38 system and reduces cccDNA by >90% at 1 ?M. GLP-26 disrupts the encapsidation of pregenomic RNA, leading to nucleocapsid disassembly and reducing the cccDNA library.
Chemical Properties
| Molecular Formula | C19H17F2N3O3 |
| Molecular Weight | 373.35 |
| CAS Numbers | 2133017-36-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1c(C(=O)C(=O)NCC#C)c(C)n(C)c1C(=O)Nc1ccc(F)c(F)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Nijampatnam B, et al. Recent advances in the development of HBV capsid assembly modulators. Curr Opin Chem Biol. 2019 Jun;50 73-79.