Toll-Like Receptor (TLR)

RS09 2TFA (1449566-36-2 free base) View larger

RS09 2TFA (1449566-36-2 free base)

ATP1938L

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HOW TO ORDER

$116.00

$116.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $52.20 Total: $5,220.00
150 $60.32 Total: $3,016.00
125 $70.76 Total: $1,769.00
110 $83.52 Total: $835.20
15 $98.60 Total: $493.00

Data sheet

Molecular FormulaC35H51F6N9O13
Molecular Weight919.82
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(O)C(F)(F)F.O=C(O)C(F)(F)F.OC[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC1=CNC=N1)NC([C@H]2N(C([C@H]3N(C([C@H](C)N)=O)CCC3)=O)CCC2)=O)=O)=O)=O
ReferencesLi et al [2016] Intranasal vaccination against HIV-1 with adenoviral vector-based nanocomplex using synthetic TLR-4 agonist peptide as adjuvant. Mol.Pharm. 13 885 PMID

More info

RS09 2TFA (1449566-36-2 free base) is a TLR4 agonist. Promotes NF-?B nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. It acts as an adjuvant in vivo and enhances X-15 specific antibody serum concentrations.