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AOB33811
CAS No: 187397-18-8
Chemical Name: N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide hydrochloride
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Availability date:
Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $17.55 | Total: $1,755.00 |
1 | 50 | $20.28 | Total: $1,014.00 |
1 | 25 | $23.79 | Total: $594.75 |
1 | 10 | $28.08 | Total: $280.80 |
1 | 5 | $33.15 | Total: $165.75 |
Molecular Formula | C27H31F3N4O7S.HCl |
Molecular Weight | 649.08 |
CAS Numbers | 187397-18-8 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
Synonym | RS-102221 HCl; RS102221 HCl; RS 102221 HCl |
IUPAC/Chemical Name | N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide hydrochloride |
InChl Key | SZJZEJZLRDIHPB-UHFFFAOYSA-N |
InChl Code | InChI=1S/C27H31F3N4O7S.ClH/c1-40-22-16-23(41-2)20(33-42(38,39)18-8-6-17(7-9-18)27(28,29)30)15-19(22)21(35)5-3-4-12-34-13-10-26(11-14-34)24(36)31-25(37)32-26;/h6-9,15-16,33H,3-5,10-14H2,1-2H3,(H2,31,32,36,37);1H |
SMILES Code | O=S(C1=CC=C(C(F)(F)F)C=C1)(NC2=CC(C(CCCCN(CC3)CCC3(NC(N4)=O)C4=O)=O)=C(OC)C=C2OC)=O.[H]Cl |
References | 1) Jahan AA, Rad A, Ghanbarabadi M, Amin B, Mohammad-Zadeh M. The role of serotonin and its receptors on the anticonvulsant effect of curcumin in pentylenetetrazol-induced seizures. Life Sci. 2018 Sep 19. pii: S0024-3205(18)30544-7. 2) Bell R, Duke AA, Gilmore PE, Page D, Bègue L. Anxiolytic-like effects observed in rats exposed to the elevated zero-maze following treatment with 5-HT2/5-HT3/5-HT4 ligands. Sci Rep. 2014 Jan 24;4:3881. |
Highly potent, selective 5-HT2C receptor antagonist