5HT Receptors

RS-102221 Hydrochloride View larger

RS-102221 Hydrochloride

AOB33811

CAS No: 187397-18-8

 

Chemical Name: N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide hydrochloride

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$39.00

$39.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $17.55 Total: $1,755.00
150 $20.28 Total: $1,014.00
125 $23.79 Total: $594.75
110 $28.08 Total: $280.80
15 $33.15 Total: $165.75

Data sheet

Molecular FormulaC27H31F3N4O7S.HCl
Molecular Weight649.08
CAS Numbers187397-18-8
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymRS-102221 HCl; RS102221 HCl; RS 102221 HCl
IUPAC/Chemical NameN-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide hydrochloride
InChl KeySZJZEJZLRDIHPB-UHFFFAOYSA-N
InChl CodeInChI=1S/C27H31F3N4O7S.ClH/c1-40-22-16-23(41-2)20(33-42(38,39)18-8-6-17(7-9-18)27(28,29)30)15-19(22)21(35)5-3-4-12-34-13-10-26(11-14-34)24(36)31-25(37)32-26;/h6-9,15-16,33H,3-5,10-14H2,1-2H3,(H2,31,32,36,37);1H
SMILES CodeO=S(C1=CC=C(C(F)(F)F)C=C1)(NC2=CC(C(CCCCN(CC3)CCC3(NC(N4)=O)C4=O)=O)=C(OC)C=C2OC)=O.[H]Cl
References1) Jahan AA, Rad A, Ghanbarabadi M, Amin B, Mohammad-Zadeh M. The role of serotonin and its receptors on the anticonvulsant effect of curcumin in pentylenetetrazol-induced seizures. Life Sci. 2018 Sep 19. pii: S0024-3205(18)30544-7.

2) Bell R, Duke AA, Gilmore PE, Page D, Bègue L. Anxiolytic-like effects observed in rats exposed to the elevated zero-maze following treatment with 5-HT2/5-HT3/5-HT4 ligands. Sci Rep. 2014 Jan 24;4:3881.

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Highly potent, selective 5-HT2C receptor antagonist