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AVE-9488
AOB6535
CAS No: 291756-32-6
Chemical Name: 2,2-Difluoro-benzo[1,3]dioxole-5-carboxylic acid indan-2-ylamide
960 Items
In stock
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.45 | Total: $157.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 100 | $16.65 | Total: $1,665.00 |
Overview
Novel enhancer of endothelial NO synthase (eNOS)
Chemical Properties
| Molecular Formula | C17H13F2NO3 |
| Molecular Weight | 317.29 |
| CAS Numbers | 291756-32-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2,2-Difluoro-benzo[1,3]dioxole-5-carboxylic acid indan-2-ylamide |
| InChl Key | OKCJNSDIVCXYAL-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H13F2NO3/c18-17(19)22-14-6-5-12(9-15(14)23-17)16(21)20-13-7-10-3-1-2-4-11(10)8-13/h1-6,9,13H,7-8H2,(H,20,21) |
| SMILES Code | O=C(C1=CC=C(OC(F)(F)O2)C2=C1)NC3CC4=C(C=CC=C4)C3 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
AVE-9488; AVE 9488; AVE9488;
References
1) Luna M, Karavitakis M. Treating portal hypertension in cirrhotic rats with AVE 9488. Liver Int. 2009 Oct;29(9):1448; author reply 1448-9.
2) Frantz S, Adamek A, Fraccarollo D, Tillmanns J, Widder JD, Dienesch C, Schäfer A, Podolskaya A, Held M, Ruetten H, Ertl G, Bauersachs J. The eNOS enhancer AVE 9488: a novel cardioprotectant against ischemia reperfusion injury. Basic Res Cardiol. 2009 Nov;104(6):773-9.
3) Schäfer A, Fraccarollo D, Widder J, Eigenthaler M, Ertl G, Bauersachs J. Inhibition of platelet activation in rats with severe congestive heart failure by a novel endothelial nitric oxide synthase transcription enhancer. Eur J Heart Fail. 2009 Apr;11(4):336-41.
