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View larger TT-10
AOB17167
CAS: 2230640-94-3
Chemical Name: (2-(Allylamino)-4-aminothiazol-5-yl)(5-fluorothiophen-2-yl)methanone
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Data sheet
| Molecular Formula | C11H10FN3OS2 |
| Molecular Weight | 283.34 |
| CAS Numbers | 2230640-94-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | TT10; TT 10; TT-10 |
| IUPAC/Chemical Name | (2-(Allylamino)-4-aminothiazol-5-yl)(5-fluorothiophen-2-yl)methanone |
| InChl Key | GVYPHJQPOHDZEI-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C11H10FN3OS2/c1-2-5-14-11-15-10(13)9(18-11)8(16)6-3-4-7(12)17-6/h2-4H,1,5,13H2,(H,14,15) |
| SMILES Code | O=C(C1=C(N)N=C(NCC=C)S1)C2=CC=C(F)S2 |
| References | 1) Hara H, et al Discovery of a Small Molecule to Increase Cardiomyocytes and Protect the Heart After Ischemic Injury. JACC Basic Transl Sci. 2018 Nov 12;3(5):639-653. 2) Ito M, et al. Characterization of a small molecule that promotes cell cycle activation of human induced pluripotent stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2019 Mar;128:90-95. |
More info
Novel activator of pro-proliferative YES-associated protein and transcriptional enhancer factor domain (YAP-TEAD) activities in cardiomyocytes, promoting cardiomyocyte proliferation and simultaneously exerting antioxidant and antiapoptotic effects in vitro
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