Allosteric

BPAM344 View larger

BPAM344

AOBS2047

CAS No: 1204572-55-3 

Chemical Name: 4-Cyclopropyl-3,4-dihydro-7-fluoro-2H-1,2,4-benzothiadiazine 1,1-dioxide

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$27.00

$27.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $12.15 Total: $1,215.00
50 $14.04 Total: $702.00
25 $16.47 Total: $411.75
10 $19.44 Total: $194.40
5 $22.95 Total: $114.75

Data sheet

Molecular FormulaC10H11FN2O2S
Molecular Weight242.27
CAS Numbers1204572-55-3
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC

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A potent positive allosteric modulator (PAM) on the three KAR subunits GluK1b, GluK2a, and GluK3a. BPAM344 potentiates glutamate-evoked currents of GluK2a 21-fold, and noticeably decreases desensitization kinetics (from 5.5 to 775 ms).