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> G Protein-Coupled Receptor Ligands>Amylin Receptor>cAC 253 acetate

Amylin Receptor

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cAC 253 acetate

ATP2135L

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$166.00

$166.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $141.10 Total: $705.50
110 $119.52 Total: $1,195.20
125 $101.26 Total: $2,531.50
150 $86.32 Total: $4,316.00
1100 $74.70 Total: $7,470.00

Data sheet

Molecular FormulaC128H206N42O42S2
Molecular Weight3069.39
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@@H](O)[C@H]1C(N[C@@H](CC2=CC=C(O)C=C2)C(N3CCC[C@H]3C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@H](C(N)=O)CSSC[C@H](N)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC5=CNC=N5)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O
ReferencesH A Coppock, et al. Rat-2 fibroblasts express specific adrenomedullin receptors, but not calcitonin-gene-related-peptide receptors, which mediate increased intracellular cAMP and inhibit mitogen-activated protein kinase activity. Biochem J. 1999 Feb 15;33

More info

cAC 253 acetate (TP2135 Free base) is an amylin antagonist. cAC 253 acetate inhibits 125I-adrenomedullin binding, with an IC50 of 25 nM.