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Overview
Nisin A is an antibacterial peptide. It is produced by the lactic acid bacterium L. lactis using uncommon amino acids, including lanthionine, and is a member of the class of antibiotics referred to as lantibiotics.
Chemical Properties
| Molecular Formula | C143H230N42O37S7 |
| Molecular Weight | 3354.07 |
| CAS Numbers | 1414-45-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1N2[C@@](CCC2)(C(=O)NCC(=O)N[C@H](C(N[C@H](C(N[C@@H]3[C@H](C)SC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]4[C@H](C)SC[C@]5(C(=O)N[C@@H](CC6=CN=CN6)C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC7=CN=CN7)C(N[C@H](C(NC(C(N[C@@H](CCCCN)C(O)=O)=O)=C)=O)[C@H](C)C)=O)=O)[C@H](CC)C)=O)CO)=O)CS[C@@H](C)[C@@](NC(=O)[C@H](C)NC4=O)(C(=O)N5)[H])[H])=O)CCCCN)=O)CCSC)=O)CC(N)=O)=O)NC(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CNC3=O)=O)CCCCN)=O)CS[C@@H](C)[C@H]1NC(=O)[C@H]8NC(=O)[C@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](NC(C(NC([C@H]([C@H](CC)C)N)=O)=CC)=O)CSC8)[H])[H] |
Storage and Handling
0C Short Term, -20C Long Term
References
Shin JM, et al. Biomedical applications of nisin. J Appl Microbiol. 2016 Jun;120[6] 1449-65.