Categories
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $141.10 | Total: $705.50 |
| 1 | 10 | $119.52 | Total: $1,195.20 |
| 1 | 25 | $101.26 | Total: $2,531.50 |
| 1 | 50 | $86.32 | Total: $4,316.00 |
| 1 | 100 | $74.70 | Total: $7,470.00 |
Overview
HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4 nM, and 107 nM, respectively. HDAC-IN-57 inhibits LSD1 with an IC50 value of 1.34 ??. HDAC-IN-57 has anti-tumor activity and can induce apoptosis.
Chemical Properties
| Molecular Formula | C21H19N3O4 |
| Molecular Weight | 377.39 |
| CAS Numbers | 2716217-79-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(NCC1=CC=C(C(NO)=O)C=C1)(=O)C=2C=C(N=CC2)C3=CC=C(OC)C=C3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Duan, Yingchao, et al. Preparation of 2-arylisonicotinamide derivatives as LSD1HDAC dual target inhibitors for treatment of acute myeloid leukemia. CN113444038