Cell Inhibition

NGI-1 View larger

NGI-1 (ML414)

AOB8262

CAS No: 790702-57-7

 

Chemical Name: ML414; 5-(dimethylsulfamoyl)-N-(5-methyl-1,3-thiazol-2-yl)-2-(pyrrolidin-1-yl)benzamide

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Molarity Calculation Cart®

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$15.00

$15.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $6.75 Total: $675.00
150 $7.80 Total: $390.00
125 $9.15 Total: $228.75
110 $10.80 Total: $108.00
15 $12.75 Total: $63.75

Data sheet

Molecular FormulaC17H22N4O3S2
Molecular Weight394.51
CAS Numbers790702-57-7
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC

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Novel cell-permeable inhibitor of oligosaccharyltransferase (OST), blocking cell-surface localization and signaling of the epidermal growth factor receptor (EGFR) glycoprotein in non-small-cell lung cancer cells, but selectively arresting proliferation in only those cell lines that are dependent on EGFR (or fibroblast growth factor, FGFR) for survival

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