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> Nuclear Receptor Ligands>CRFR>Astressin acetate

CRFR

Astressin acetate View larger

Astressin acetate

ATP1448L

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$201.00

$201.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $170.85 Total: $854.25
110 $144.72 Total: $1,447.20
125 $122.61 Total: $3,065.25
150 $104.52 Total: $5,226.00
1100 $90.45 Total: $9,045.00

Data sheet

Molecular FormulaC163H273N49O44
Molecular Weight3623.21
CAS Numbers2064121-65-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(O)=O.O=C(O)CC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](N)CC1=CC=CC=C1)=O)CC2=CNC=N2)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)C(C)C)=O)CC(C)C)=O)CCC(O)=O)=O)CCCC)=O)C)=O)CCCNC(N)=N)=O)C)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC3)C(N[C@@H](C)C(N[C@@H](CC4=CNC=N4)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCCC)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCCCNC3=O)=O)=O)=O)=O)=O)=O)=O)=O
ReferencesMaecker H, et al. Astressin, a novel and potent CRF antagonist, is neuroprotective in the hippocampus when administered after a seizure. Brain Res. 1997 Jan 2;744[1] 166-70.

More info

Astressin acetate is an antagonist of corticotropin releasing factor (CRF) with low affinity for the CRF binding protein and high affinity for the cloned pituitary receptor(Ki = 2 nM).