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View larger Vildagliptin
AOB0436
CAS 274901-16-5
Chemical Name: NVP-LAF237; LAF237; (S)-1-[N-(3-Hydroxy-1-adamantyl)glycyl]pyrrolidine-2-carbonitrile
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | 25 mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $29.75 | Total: $148.75 |
| 1 | 10 | $25.20 | Total: $252.00 |
| 1 | 25 | $21.35 | Total: $533.75 |
| 1 | 50 | $18.20 | Total: $910.00 |
| 1 | 100 | $15.75 | Total: $1,575.00 |
Data sheet
| Molecular Formula | C17H25N3O2 |
| Molecular Weight | 303.4 |
| CAS Numbers | 274901-16-5 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | LAF237; NVP-LAF237 |
| IUPAC/Chemical Name | 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2S-pyrrolidinecarbonitrile |
| InChl Key | SYOKIDBDQMKNDQ-QWJLZPNVSA-N |
| InChl Code | InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14?,16-,17- |
| SMILES Code | O=C(CN[C@@]1(CC(C2)C3)CC3C[C@]2(O)C1)N4[C@H](C#N)CCC4 |
| References | 1) Ikuma, Y., Hochigai, H., Kimura, H., et al. Discovery of 3H-imidazol[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitors. Bioorg. Med. Chem. 20(19), 5864-5883 (2012). 2) Burkey, B.F., Li, X., Bolognese, L., et al. Acute and chronic effects of the incretin enhancer vildagliptin in insulin-resistant rats. J. Pharmacol. Exp. Ther. 315(2), 688-695 (2005). |
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Dipeptidyl peptidase-4 (DPP-4) inhibitor