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Cyclic Nucleotide Turnover Enzymes
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Palbociclib (PD0332991) Bulk
AOB87334
CAS No:571190-30-2
Chemical Name: PD0332991
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity (mg or Unit) | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|
| 100 | $6.75 | Total: $675.00 |
| 50 | $7.80 | Total: $390.00 |
| 25 | $9.15 | Total: $228.75 |
| 10 | $10.80 | Total: $108.00 |
| 5 | $12.75 | Total: $63.75 |
Data sheet
| Molecular Formula | C24H29N7O2 |
| Molecular Weight | 447.53 |
| CAS Numbers | 571190-30-2 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 99% (HPLC) |
| Synonym | PD-0332991; PD 0332991; PD0332991; Palbociclib free base, brand name: Ibrance. |
| IUPAC/Chemical Name | 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one |
| InChl Key | AHJRHEGDXFFMBM-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H29N7O2/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29) |
| SMILES Code | O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5 |
| References | 1) LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Available from http://www.ncbi.nlm.nih.gov/books/NBK547882/ PubMed PMID: 31643218. 2) Serra F, Lapidari P, Quaquarini E, Tagliaferri B, Sottotetti F, Palumbo R. Palbociclib in metastatic breast cancer: current evidence and real-life data. Drugs Context. 2019 Jul 16;8:212579. doi: 10.7573/dic.212579. eCollection 2019. Review. PubMed PMID: 31391852; PubMed Central PMCID: PMC6668507. |
More info
An orally bioavailable, potent and highly selective cyclindependent kinase 4 and 6 (CDK 4 and 6)
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