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UBP141
AOB4736
CAS No: 344768-30-5
Chemical Name: cis-1-(Phenanthrene-3-carbonyl)-piperazine-2,3-dicarboxylic acid; UBP-141
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.45 | Total: $157.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 100 | $16.65 | Total: $1,665.00 |
Overview
Novel NR2D-preferring antagonist inhibiting NMDA-EPSCs
Chemical Properties
| Molecular Formula | C21H18N2O5 |
| Molecular Weight | 378.38 |
| CAS Numbers | 344768-30-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (2R,3S)-1-[(phenanthren-3-yl)carbonyl]piperazine-2,3-dicarboxylic acid |
| InChl Key | VVUAQPXBYDYTDF-ZWKOTPCHSA-N |
| InChl Code | InChI=1S/C21H18N2O5/c24-19(23-10-9-22-17(20(25)26)18(23)21(27)28)14-8-7-13-6-5-12-3-1-2-4-15(12)16(13)11-14/h1-8,11,17-18,22H,9-10H2,(H,25,26)(H,27,28)/t17-,18+/m0/s1 |
| SMILES Code | O=C([C@@H]1N(C(C2=CC=C3C=CC4=CC=CC=C4C3=C2)=O)CCN[C@@H]1C(O)=O)O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
UBP141, UBP 141, UBP-141
References
1) Yamamoto H, Kamegaya E, Sawada W, Hasegawa R, Yamamoto T, Hagino Y, Takamatsu Y, Imai K, Koga H, Mishina M, Ikeda K. Involvement of the N-methyl-D-aspartate receptor GluN2D subunit in phencyclidine-induced motor impairment, gene expression, and increased Fos immunoreactivity. Mol Brain. 2013 Dec 16;6:56.
2) Wang M, Chazot PL, Ali S, Duckett SF, Obrenovitch TP. Effects of NMDA receptor antagonists with different subtype selectivities on retinal spreading depression. Br J Pharmacol. 2012 Jan;165(1):235-44.