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AOB37914
CAS: 1026791-61-6
Chemical Name: (3S)-3,4-Propano-2,3-dihydropyrido[3,2-f][1,4]oxazepine-5(4H)-one
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Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $11.25 | Total: $1,125.00 |
1 | 50 | $13.00 | Total: $650.00 |
1 | 25 | $15.25 | Total: $381.25 |
1 | 10 | $18.00 | Total: $180.00 |
1 | 5 | $21.25 | Total: $106.25 |
Molecular Formula | C11H12N2O2 |
Molecular Weight | 204.23 |
CAS Numbers | 1026791-61-6 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO and Alcohol |
Purity | 98% by HPLC |
Synonym | Org-26576; Org26576; Org 26576 |
IUPAC/Chemical Name | (3S)-3,4-Propano-2,3-dihydropyrido[3,2-f][1,4]oxazepine-5(4H)-one |
InChl Key | FIKUEZUFASUKAH-QMMMGPOBSA-N |
InChl Code | InChI=1S/C11H12N2O2/c14-11-9-4-1-5-12-10(9)15-7-8-3-2-6-13(8)11/h1,4-5,8H,2-3,6-7H2/t8-/m0/s1 |
SMILES Code | O=C1N(CCC2)[C@]2([H])COC3=NC=CC=C13 |
References | 1) Nations KR, et al L. Examination of Org 26576, an AMPA receptor positive allosteric modulator, in patients diagnosed with major depressive disorder: an exploratory, randomized, double-blind, placebo-controlled trial. J Psychopharmacol. 2012 Dec;26(12):1525-39. doi: 10.1177/0269881112458728. PubMed PMID: 22954616. 2) Nations KR, et al., Maximum tolerated dose evaluation of the AMPA modulator Org 26576 in healthy volunteers and depressed patients: a summary and method analysis of bridging research in support of phase II dose selection. Drugs R D. 2012 Sep 1;12(3):127-39. doi: 10.2165/11634360-000000000-00000. PubMed PMID: 22852579; PubMed Central PMCID: PMC3585695. |
Novel AMPA receptor positive allosteric modulator