Enzyme Inhibitors

BV02 View larger

BV02

AOB17338

CAS No: 292870-53-2

 

Chemical Name: 2-((1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)carbamoyl)terephthalic acid

More details

Molarity Calculation Cart®

HOW TO ORDER

$59.00

$59.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $26.55 Total: $2,655.00
150 $30.68 Total: $1,534.00
125 $35.99 Total: $899.75
110 $42.48 Total: $424.80
15 $50.15 Total: $250.75

Data sheet

Molecular FormulaC20H19N3O5
Molecular Weight377.36
CAS Numbers292870-53-2
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymBV 02; BV 02; BV02
IUPAC/Chemical Name2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid
InChl KeyZFYSDSINNOLWGO-UHFFFAOYSA-N
InChl CodeInChI=1S/C20H15N3O5/c1-11-16(19(26)23(21(11)2)13-6-4-3-5-7-13)22-17(24)14-9-8-12(20(27)28)10-15(14)18(22)25/h3-10H,1-2H3,(H,27,28)
SMILES CodeO=C1N(C2=CC=CC=C2)N(C)C(C)=C1N3C(C(C=C(C(O)=O)C=C4)=C4C3=O)=O
References1) Iralde-Lorente L, Cau Y, Clementi L, Franci L, Tassone G, Valensin D, Mori M, Angelucci A, Chiariello M, Botta M. Chemically stable inhibitors of 14-3-3 protein-protein interactions derived from BV02. J Enzyme Inhib Med Chem. 2019 Dec;34(1):657-664.

2) Root A, Beizaei A, Ebhardt HA. Structure-based assessment and network analysis of targeting 14-3-3 proteins in prostate cancer. Mol Cancer. 2018 Oct 31;17(1):156.

More info

Novel inhibitor of SFN, also targeting YWHAZ of the 14-3-3 protein family

Customers who bought this product also bought: