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LEM-14
AOB36084
CAS: 1814881-70-3
Chemical Name: (R)-2-((4-(1-Oxoisochromane-3-carbonyl)piperazin-1-yl)methyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one
1962 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $50.15 | Total: $250.75 |
| 1 | 10 | $42.48 | Total: $424.80 |
| 1 | 25 | $35.99 | Total: $899.75 |
| 1 | 50 | $30.68 | Total: $1,534.00 |
| 1 | 100 | $26.55 | Total: $2,655.00 |
Overview
Novel specific NSD2 inhibitor
Chemical Properties
| Molecular Formula | C25H28N4O4S |
| Molecular Weight | 478.57 |
| CAS Numbers | 1814881-70-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (R)-2-((4-(1-Oxoisochromane-3-carbonyl)piperazin-1-yl)methyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one |
| InChl Key | ZJOXWRFJOUWUKX-GOSISDBHSA-N |
| InChl Code | InChI=1S/C25H26N4O4S/c30-22-21-17-7-3-4-8-19(17)34-23(21)27-20(26-22)14-28-9-11-29(12-10-28)24(31)18-13-15-5-1-2-6-16(15)25(32)33-18/h1-2,5-6,18H,3-4,7-14H2,(H,26,27,30)/t18-/m1/s1 |
| SMILES Code | O=C1C(C2=C(CCCC2)S3)=C3N=C(CN4CCN(C([C@@H](CC5=C6C=CC=C5)OC6=O)=O)CC4)N1 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
LEM14; LEM 14; LEM-14
References
Shen Y, Morishita M, Lee D, Kim S, Lee T, Mevius DEHF, Roh Y, di Luccio E. Identification of LEM-14 inhibitor of the oncoprotein NSD2. Biochem Biophys Res Commun. 2019 Jan 1;508(1):102-108
