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GS-441524 Solution
AOB36496S
CAS No: 1191237-69-0
Quantity = mL (each mL contain 10 mg of GS-441524)
1527 Items
This product is intended for scientific researcher only
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mL | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Overview
GS-441524 solution (10 mg/mL) is ready to use solution in FIP study, that was prepared according to a published procedure by Dr. Pederson in Journal of Feline Med. Surg. 21:271-281 (2019.
Chemical Properties
| Molecular Formula | C12H13N5O4 |
| Molecular Weight | 291.27 |
| CAS Numbers | 1191237-69-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile |
| InChl Key | BRDWIEOJOWJCLU-LTGWCKQJSA-N |
| InChl Code | InChI=1S/C12H13N5O4/c13-4-12(10(20)9(19)7(3-18)21-12)8-2-1-6-11(14)15-5-16-17(6)8/h1-2,5,7,9-10,18-20H,3H2,(H2,14,15,16)/t7-,9-,10-,12+/m1/s1 |
| SMILES Code | N#C[C@@]1(C2=CC=C3C(N)=NC=NN32)O[C@H](CO)[C@@H](O)[C@H]1O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Pedersen NC, Perron M, Bannasch M, Montgomery E, Murakami E, Liepnieks M, Liu H. Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis. J Feline Med Surg. 2019 Apr;21(4):271-281.
2) Murphy BG, Perron M, Murakami E, Bauer K, Park Y, Eckstrand C, Liepnieks M, Pedersen NC. The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. Vet Microbiol. 2018 Jun;219:226-233.
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