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> Pathway Inhibitors>Enzyme Inhibitors>Vardenafil hydrochloride trihydrate

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Vardenafil hydrochloride trihydrate

AOB14408

CAS: 330808-88-3

 

Chemical Name: 2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one dihydrochloride trihydrate

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QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $9.35 Total: $46.75
110 $7.92 Total: $79.20
125 $6.71 Total: $167.75
150 $5.72 Total: $286.00
1100 $4.95 Total: $495.00

Data sheet

Molecular FormulaC23H40Cl2N6O7S
Molecular Weight615.57
CAS Numbers330808-88-3
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymBAY 38-9456; BAY-38-9456; BAY38-9456; Vardenafil hydrochloride trihydrate; Vardenafil HCl; Levitra; Staxyn; Vivanza
IUPAC/Chemical Name2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one dihydrochloride trihydrate
InChl KeyNEAUGLIJDBPHAY-UHFFFAOYSA-N
InChl CodeInChI=1S/C23H32N6O4S.2ClH.3H2O/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;;;;;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);2*1H;3*1H2
SMILES CodeO=C1N=C(C2=CC(S(=O)(N3CCN(CC)CC3)=O)=CC=C2OCC)NN4C1=C(C)N=C4CCC.[H]Cl.[H]Cl.[H]O[H].[H]O[H].[H]O[H]
References1) Ashour AE, Rahman AF, Kassem MG. Vardenafil dihydrochloride. Profiles Drug Subst Excip Relat Methodol. 2014;39:515-44. doi: 10.1016/B978-0-12-800173-8.00009-X. Review. PubMed PMID: 24794912.

2) Gamidov SI, Iremashvili VV, Popova AIu. [Modernity in the treatment of erectile dysfunction: Levitra (vardenafil) in the form of oral dispersible tablet]. Urologiia. 2013 May-Jun;(3):102-4, 106. Review. Russian. PubMed PMID: 23987060.

More info

A PDE5 inhibitor used for treating erectile dysfunction. Vardenafil (VAR) is synthetic, highly selective, and potent inhibitor of phosphodiesterase-5 which competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. It is clinically approved for treatment of erectile dysfunction in men, including diabetic and postprostatectomy patients.