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OSMI-1

Cat No: AOB5700

Condition

CAS No: 1681056-61-0

Chemical Name: (R)-N-(Furan-2-ylmethyl)-2-(2-methoxyphenyl)-2-(2-oxo-1,2-dihydroquinoline-6-sulfonamido)-N-(thiophen-2-ylmethyl)acetamide

AOBIOUS launched this product in 2015

CITATIONS - Publications That Use AOBIOUS Product

1) O-GlcNAcylation enhances the tumorigenic properties of cervical cancer cells in vitro

2) Cell Reports 20(5):1088-1099 · August 2017

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6853 Item Items

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Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	5	$24.52	Total: $122.61
1	10	$20.77	Total: $207.72
1	25	$17.60	Total: $439.96
1	50	$15.00	Total: $750.10
1	100	$12.98	Total: $1,298.25

Data sheet

Molecular Formula	C28H25N3O6S2
Molecular Weight	563.64
CAS Numbers	1681056-61-0
Storage Condition	0°C (short term), -20°C (long term), desiccated
Solubility	DMSO
Purity	98% by HPLC
Synonym	OSMI-1; OSMI 1; OSMI1
IUPAC/Chemical Name	αR-[[(1,2-dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)-benzeneacetamide
InChl Key	IYIGLWQQAMROOF-HHHXNRCGSA-N
InChl Code	InChI=1S/C28H25N3O6S2/c1-36-25-9-3-2-8-23(25)27(28(33)31(17-20-6-4-14-37-20)18-21-7-5-15-38-21)30-39(34,35)22-11-12-24-19(16-22)10-13-26(32)29-24/h2-16,27,30H,17-18H2,1H3,(H,29,32)/t27-/m1/s1
SMILES Code	O=C([C@@H](C1=CC=CC=C1OC)NS(C2=CC(C=CC(N3)=O)=C3C=C2)(=O)=O)N(CC4=CC=CO4)CC5=CC=CS5
References	1) Park SK, et al. A Conserved Splicing Silencer Dynamically Regulates O-GlcNAc Transferase Intron Retention and O-GlcNAc Homeostasis. Cell Rep. 2017 Aug 1;20(5):1088-1099. 2) Angelova M, et al. Inhibition of O-Linked N-Acetylglucosamine Transferase Reduces Replication of Herpes Simplex Virus and Human Cytomegalovirus. J Virol. 2015 Aug;89(16):8474-83. 3) Ortiz-Meoz, R.F., Jiang, J., Lazarus, M.B., et al. A small molecule that inhibits OGT activity in cells. ACS Chem Biol. 10(6), 1392-1397 (2015).