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OTUB1/USP8 inhibitor 61
AOB15495
CAS: 2858800-98-1
Chemical Name: (R)-2-(2-Chloro-6-fluoro-3-((1-methylpyrrolidin-3-yl)oxy)phenyl)naphtho[2,3-d]oxazole-4,9-dione
999 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $33.15 | Total: $165.75 |
| 1 | 10 | $28.08 | Total: $280.80 |
| 1 | 25 | $23.79 | Total: $594.75 |
| 1 | 50 | $20.28 | Total: $1,014.00 |
| 1 | 100 | $17.55 | Total: $1,755.00 |
Overview
Novel Potent OTUB1/USP8 Dual Inhibitor, Targeting Proteostasis in Non-Small-Cell Lung Cancer
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00408
Chemical Properties
| Molecular Formula | C22H16ClFN2O4 |
| Molecular Weight | 426.82 |
| CAS Numbers | 2858800-98-1 |
| Solubility | DMSO and Water |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (R)-2-(2-Chloro-6-fluoro-3-((1-methylpyrrolidin-3-yl)oxy)phenyl)naphtho[2,3-d]oxazole-4,9-dione |
| SMILES Code | O=C(C1=C2OC(C3=C(F)C=CC(O[C@H]4CN(C)CC4)=C3Cl)=N1)C5=C(C=CC=C5)C2=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
OTUB1/USP8-IN-1
References
1) Tan L, et, al. Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer. J Med Chem. 2022 Oct 11
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