Enzyme Inhibitors

OTUB1/USP8 inhibitor 61 View larger

OTUB1/USP8 inhibitor 61

AOB15495

CAS: 2858800-98-1

 

Chemical Name: (R)-2-(2-Chloro-6-fluoro-3-((1-methylpyrrolidin-3-yl)oxy)phenyl)naphtho[2,3-d]oxazole-4,9-dione

More details

Molarity Calculation Cart®

HOW TO ORDER

$39.00

$39.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $17.55 Total: $1,755.00
150 $20.28 Total: $1,014.00
125 $23.79 Total: $594.75
110 $28.08 Total: $280.80
15 $33.15 Total: $165.75

Data sheet

Molecular FormulaC22H16ClFN2O4
Molecular Weight426.82
CAS Numbers2858800-98-1
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Water
Purity98% by HPLC
SynonymOTUB1/USP8-IN-1
IUPAC/Chemical Name(R)-2-(2-Chloro-6-fluoro-3-((1-methylpyrrolidin-3-yl)oxy)phenyl)naphtho[2,3-d]oxazole-4,9-dione
SMILES CodeO=C(C1=C2OC(C3=C(F)C=CC(O[C@H]4CN(C)CC4)=C3Cl)=N1)C5=C(C=CC=C5)C2=O
References1) Tan L, et, al. Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer. J Med Chem. 2022 Oct 11

More info

Novel Potent OTUB1/USP8 Dual Inhibitor, Targeting Proteostasis in Non-Small-Cell Lung Cancer

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00408

 

Customers who bought this product also bought: